GAMMA CARBOXYGLUTAMATE Meaning and
Definition
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Gamma carboxyglutamate is a post-translationally modified amino acid that plays a significant role in various biological processes. It is derived from the amino acid glutamic acid through a process known as carboxylation. In this process, an enzyme known as γ-glutamyl carboxylase adds a carboxyl group to the gamma carbon of glutamic acid, resulting in the formation of gamma carboxyglutamate.
Gamma carboxyglutamate is primarily involved in the activation and regulation of calcium binding proteins, particularly in the blood clotting cascade and the formation of bone tissue. In blood clotting, gamma carboxyglutamate plays a crucial role in the activation of coagulation factors, such as prothrombin, which eventually leads to the formation of a blood clot to stop bleeding. Additionally, gamma carboxyglutamate is found in various bone and tooth proteins, where it aids in the mineralization process for the development and maintenance of healthy bones and teeth.
Due to its importance in calcium binding and regulation, gamma carboxyglutamate has also been implicated in other physiological processes, including neuronal signaling, immune response, and cell adhesion. Abnormal levels or defects in the carboxylation process of glutamic acid can lead to various health conditions, such as bleeding disorders and abnormalities in bone and tooth formation.
In summary, gamma carboxyglutamate is a modified amino acid that plays a crucial role in calcium binding, blood clotting, bone formation, and other physiological processes in the body.
Common Misspellings for GAMMA CARBOXYGLUTAMATE
- famma carboxyglutamate
- vamma carboxyglutamate
- bamma carboxyglutamate
- hamma carboxyglutamate
- yamma carboxyglutamate
- tamma carboxyglutamate
- gzmma carboxyglutamate
- gsmma carboxyglutamate
- gwmma carboxyglutamate
- gqmma carboxyglutamate
- ganma carboxyglutamate
- gakma carboxyglutamate
- gajma carboxyglutamate
- gamna carboxyglutamate
- gamka carboxyglutamate
- gamja carboxyglutamate
- gammz carboxyglutamate
- gamms carboxyglutamate
- gammw carboxyglutamate
- gammq carboxyglutamate
Etymology of GAMMA CARBOXYGLUTAMATE
The word "gamma carboxyglutamate" is a scientific term derived from the combination of the Greek letter "gamma" (γ), the word "carboxy", which refers to the carboxyl group (-COOH) attached to the glutamate molecule, and "glutamate", which is a naturally occurring amino acid.
The term "gamma" is derived from the third letter of the Greek alphabet, which signifies the third position of the carboxyl group on the glutamate molecule. "Carboxy" is a prefix derived from the Greek word "karbos", meaning "coal" or "charcoal", referring to the carbon atoms in the carboxyl group. "Glutamate" comes from the Latin word "glutinare", which means "to glue" or "to adhere", as glutamate was initially isolated from the protein gluten.
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