HSN TYPE II Meaning and
Definition
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HSN Type II is a medical term referring to a specific subtype of hereditary sensory neuropathy (HSN). Hereditary sensory neuropathy is a group of inherited disorders that affect the peripheral nerves responsible for transmitting sensory information, such as pain, temperature, touch, and body position, from the body to the brain.
HSN Type II is characterized by its onset in infancy or early childhood. Individuals with this type of HSN typically experience progressive loss of sensation, primarily affecting the lower limbs, before spreading to other areas of the body. This sensory loss often leads to difficulties with balance and coordination. As the condition progresses, individuals may also develop muscle weakness and atrophy.
Genetically, HSN Type II is inherited in an autosomal recessive manner, meaning that both parents must carry a copy of the mutated gene for their child to be affected. The condition is associated with mutations in the WNK1 gene, which is responsible for encoding a protein involved in the regulation of ion channels.
Diagnosis of HSN Type II usually involves a thorough clinical examination, evaluation of symptoms, and genetic testing to confirm the presence of WNK1 gene mutations. Treatment for HSN Type II typically focuses on managing symptoms and improving quality of life. This may involve physical and occupational therapy to address motor and functional impairments, assistive devices such as braces or orthotics, and pain management strategies. Genetic counseling may also be recommended for affected individuals and their families to understand the inheritance pattern and potential risks for future generations.
Common Misspellings for HSN TYPE II
- hsn typei
- gsn type ii
- bsn type ii
- nsn type ii
- jsn type ii
- usn type ii
- ysn type ii
- hzn type ii
- hxn type ii
- hdn type ii
- hen type ii
- hwn type ii
- hsb type ii
- hsm type ii
- hsj type ii
- hsh type ii
- hsn rype ii
- hsn fype ii
- hsn gype ii
- hsn yype ii
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