PHENYLMETHYLSULFONYL FLUORIDE Meaning and
Definition
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Phenylmethylsulfonyl fluoride (PMSF) is a commonly used chemical compound in biochemical research and laboratory settings. It is a synthetic compound belonging to the group of organosulfur compounds.
PMSF is an odorless, colorless solid that is soluble in various organic solvents. It is derived from benzene, with a phenyl group attached to a methyl group, and a sulfonyl fluoride functional group. This compound is known for its strong inhibitory properties against a range of proteases, making it a valuable tool in enzymological studies.
In biochemistry, PMSF is often used as a serine protease inhibitor. It works by reacting with the active site of serine proteases, forming a stable complex and irreversibly blocking the enzymatic activity. This property makes PMSF suitable for protecting proteins from degradation during purification processes or when studying proteinaceous substances.
Furthermore, PMSF is utilized in the extraction and analysis of proteins, particularly for research involving membrane proteins. It effectively prevents the degradation of these proteins by endogenous proteases present in cell membranes.
However, it is important to note that PMSF is highly toxic and cautions must be taken when handling it. It is an irritant to the skin, eyes, and respiratory system. Adequate protective measures should be implemented, such as wearing gloves, goggles, and a lab coat, and working in a well-ventilated area.
Common Misspellings for PHENYLMETHYLSULFONYL FLUORIDE
- ohenylmethylsulfonyl fluoride
- lhenylmethylsulfonyl fluoride
- -henylmethylsulfonyl fluoride
- 0henylmethylsulfonyl fluoride
- pgenylmethylsulfonyl fluoride
- pbenylmethylsulfonyl fluoride
- pnenylmethylsulfonyl fluoride
- pjenylmethylsulfonyl fluoride
- puenylmethylsulfonyl fluoride
- pyenylmethylsulfonyl fluoride
- phwnylmethylsulfonyl fluoride
- phsnylmethylsulfonyl fluoride
- phdnylmethylsulfonyl fluoride
- phrnylmethylsulfonyl fluoride
- ph4nylmethylsulfonyl fluoride
- ph3nylmethylsulfonyl fluoride
- phebylmethylsulfonyl fluoride
- phemylmethylsulfonyl fluoride
- phejylmethylsulfonyl fluoride
- phehylmethylsulfonyl fluoride
Etymology of PHENYLMETHYLSULFONYL FLUORIDE
The word "Phenylmethylsulfonyl Fluoride" is a chemical compound name, and its etymology can be broken down as follows:
1. Phenyl: This term comes from the ancient Greek word "phainó", meaning "to show" or "to shine". It is often used as a prefix in chemistry to indicate a compound containing a benzene ring.
2. Methyl: This term is derived from "methy", which comes from the Latin word "meticulum" meaning "wine made from sweet grapes". In chemistry, "methyl" refers to a chemical group containing one carbon atom bonded to three hydrogen atoms (-CH3).
3. Sulfonyl: This term originates from "sulfonic acid", which is derived from "sulfur".
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