PHOSPHOLIPASE C Meaning and
Definition
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Phospholipase C is an enzyme that plays a crucial role in the regulation of various cellular processes in living organisms. It is a class of enzymes that acts upon phospholipids, which are a major component of cell membranes. The primary function of phospholipase C is to cleave phospholipids into two molecules: diacylglycerol (DAG), and inositol trisphosphate (IP3).
When activated, phospholipase C catalyzes the hydrolysis of the lipid portion of phospholipids, resulting in the release of DAG and IP3. These secondary messengers are then able to modulate cellular responses by interacting with specific proteins and triggering various signaling pathways. Diacylglycerol plays an important role in the activation of protein kinase C (PKC), which in turn regulates multiple cellular functions such as cell growth, differentiation, and programmed cell death.
Inositol trisphosphate acts by binding to specific receptors on the endoplasmic reticulum, leading to the release of calcium ions into the cytoplasm, thereby initiating a cascade of events involved in the regulation of gene expression, cellular metabolism, and neurotransmitter release.
Phospholipase C is found in various organisms, including bacteria, yeast, plants, and animals. It is involved in diverse physiological processes, including neurotransmission, muscle contraction, immune responses, and hormone secretion. Dysregulation or mutations in the genes encoding phospholipase C have been associated with various diseases, including cancer, diabetes, neurological disorders, and immune system abnormalities.
Common Misspellings for PHOSPHOLIPASE C
- ohospholipase c
- lhospholipase c
- -hospholipase c
- 0hospholipase c
- pgospholipase c
- pbospholipase c
- pnospholipase c
- pjospholipase c
- puospholipase c
- pyospholipase c
- phispholipase c
- phkspholipase c
- phlspholipase c
- phpspholipase c
- ph0spholipase c
- ph9spholipase c
- phoapholipase c
- phozpholipase c
- phoxpholipase c
- phodpholipase c
Etymology of PHOSPHOLIPASE C
The word "Phospholipase C" is derived from combining different elements and terms.
1. Phospholipase: The term "phospholipase" is derived from "phospho-", which signifies the presence of phosphorus, and "lipase", which refers to an enzyme that breaks down lipids (fats). In this context, phospholipases act on phospholipids by cleaving them into their constituent molecules.
2. C: The letter "C" in "Phospholipase C" denotes one of the subtypes of phospholipase enzymes. Phospholipase C is categorized into different subtypes (e.g., Phospholipase C-alpha, Phospholipase C-beta, etc.), which are designated by letters or numbers to differentiate them based on their characteristics and functions.
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